Low stromal Foxp3+ regulatory T-cell density is associated with complete response to neoadjuvant chemoradiotherapy in rectal cancer

Low stromal Foxp3+ regulatory T-cell density is associated with complete response to neoadjuvant chemoradiotherapy in rectal cancer

© 2015 Cancer Research UK Background:Foxp3+ regulatory T cells (Tregs) play a vital role in preventing autoimmunity, but also suppress antitumour immune responses. Tumour infiltration by Tregs has strong prognostic significance in colorectal cancer, and accumulating evidence suggests that chemothera...

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Bibliographic Details
Main Authors: McCoy, M., Hemmings, C., Miller, T., Austin, S., Bulsara, M., Zeps, Nikolajs, Nowak, A., Lake, R., Platell, C.
Format: Journal Article
Published: 2015
Online Access:http://hdl.handle.net/20.500.11937/27135

Internet

http://hdl.handle.net/20.500.11937/27135

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