Relationship between surface concentration of l-leucine and bulk powder properties in spray dried formulations

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Relationship between surface concentration of l-leucine and bulk powder properties in spray dried formulations

The amino acid l-leucine has been demonstrated to act as a lubricant and improve the dispersibility of otherwise cohesive fine particles. It was hypothesized that optimum surface l-leucine concentration is necessary to achieve optimal surface and bulk powder properties. Polyvinylpyrrolidone was spra...

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Bibliographic Details
Main Authors:	Mangal, S., Meiser, F., Tan, G., Gengenbach, T., Denman, J., Rowles, Matthew, Larson, I., Morton, D.
Format:	Journal Article
Published:	2015
Subjects:	- Inter-particle cohesion - Spray drying L-Leucine - Polyvinylpyrrolidone - Surface mapping
Online Access:	http://hdl.handle.net/20.500.11937/2700

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