Relationship between surface concentration of l-leucine and bulk powder properties in spray dried formulations
The amino acid l-leucine has been demonstrated to act as a lubricant and improve the dispersibility of otherwise cohesive fine particles. It was hypothesized that optimum surface l-leucine concentration is necessary to achieve optimal surface and bulk powder properties. Polyvinylpyrrolidone was spra...
| Main Authors: | , , , , , , , |
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| Format: | Journal Article |
| Published: |
2015
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/2700 |