FTIR imaging of brain tissue reveals crystalline creatine deposits are an ex vivo marker of localized ischemia during murine cerebral malaria: General implications for disease neurochemistry

Phosphocreatine is a major cellular source of high energy phosphates, which is crucial to maintain cell viability under conditions of impaired metabolic states, such as decreased oxygen and energy availability (i.e., ischemia). Many methods exist for the bulk analysis of phosphocreatine and its deph...

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Bibliographic Details
Main Authors: Hackett, Mark, Lee, J., El-Assaad, F., McQuillan, J., Carter, E., Grau, G., Hunt, N., Lay, P.
Format: Journal Article
Published: American Chemical Society 2012
Online Access:http://hdl.handle.net/20.500.11937/2686