Structural biology of carbohydrate xenoantigens

Transplantation of organs across species (xenotransplantation) is being considered to overcome the shortage of human donor organs. However, unmodified pig organs undergo an antibody-mediated hyperacute rejection that is brought about by the presence of natural antibodies to Gala(1,3)Gal, which is th...

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Bibliographic Details
Main Authors: Yuriev, E., Agostino, Mark, Farrugia, W., Christiansen, D., Sandrin, M., Ramsland, Paul
Format: Journal Article
Published: Informa Healthcare 2009
Online Access:http://hdl.handle.net/20.500.11937/26168