The synthesis and biological evaluation of novel analogues of isocryptolepine

This thesis investigates the potential of the alkaloid isocryptolepine 16 as a lead compound in antimalarial drug development. Fifteen derivatives of the parent alkaloid were prepared and fully characterised, twelve of which were novel compounds. A select group of compounds were subsequently evaluat...

Full description

Bibliographic Details
Main Author: Whittell, Louise Renee'
Format: Thesis
Language:English
Published: Curtin University 2011
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/2558