Gliclazide reduces MKC intestinal transport in healthy but not diabetic rats

Gliclazide reduces MKC intestinal transport in healthy but not diabetic rats

The aim is to investigate the influence of the antidiabetic drug gliclazide on the ileal permeation of the semisynthetic bile acid, MKC, in tissues from healthy and diabetic rats. Sixteen Wistar rats (350 +/- 50 g) were randomly allocated into four groups (4 rats per group, 8 chambers per rat, i.e.,...

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Bibliographic Details
Main Authors: Al-Salami, Hani, Butt, G., Tucker, I., Fawcett, P., Golocorbin-Kon, S., Mikov, I., Mikov, M.
Format: Journal Article
Published: Springer France 2009
Subjects:
permeation
Mrp3
transporters
gliclazide
diabetes
bile acid
Online Access:http://hdl.handle.net/20.500.11937/25466

Internet

http://hdl.handle.net/20.500.11937/25466

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