Predicting the parasite killing effect of artemisinin combination therapy in a murine malaria model
Objectives: To develop a mechanism-based model that describes the time course of the malaria parasite in infected mice receiving a combination therapy regimen of dihydroartemisinin and piperaquine. Methods: Total parasite density–time data from Swiss mice inoculated with Plasmodium berghei were used...
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Published: |
Oxford University Press
2014
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/24949 |