Low-Dose Sublingual Ketamine Does Not Modulate Experimentally Induced Mechanical Hyperalgesia in Healthy Subjects

Objective: Musculoskeletal pain has been associated with N-methyl-d-aspartate (NMDA) receptor-mediated mechanisms. This randomized controlled trial (RCT) investigated the effect of the NMDA receptor antagonist ketamine (25 mg sublingually) on modulating experimental muscle pain. Design: Two groups (...

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Bibliographic Details
Main Authors: Slater, Helen, Graven-Neilsen, T., Wright, Anthony, Schug, S.
Format: Journal Article
Published: Wiley-Blackwell Publishing, Inc 2012
Online Access:http://hdl.handle.net/20.500.11937/24474