In utero smoke exposure and role of maternal and infant glutathione S-transferase genes on airway responsiveness and lung function in infancy

Rationale: Xenobiotics in the maternal circulation are capable of crossing the placental barrier so a reduction in the mother and fetus's detoxification ability due to genetic variation in the glutathione S-transferases (GSTs) could expose the fetus to higher levels of toxins. Objectives: To in...

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Bibliographic Details
Main Authors: Murdzoska, J., Devadason, S., Khoo, S., Landau, L., Young, S., Goldblatt, J., Zhang, Guicheng, Le Souëf, P., Hayden, C.
Format: Journal Article
Published: American Thoracic Society 2010
Online Access:http://hdl.handle.net/20.500.11937/24274