Dz13, a c-jun DNAzyme, Is a Potent Inducer of Caspase-2 Activation
Signaling pathways for caspase-2-mediated apoptosis are poorly defined. This is partially due to a lack of a reproducible stimulus to trigger caspase-2 activation. We present the oligonucleotide Dz13, a DNA enzyme that cleaves c-Jun mRNA and is capable of inhibiting various model tumors in mice, whi...
| Main Authors: | , , |
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| Format: | Journal Article |
| Published: |
Mary Ann Liebert inc
2010
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| Online Access: | http://hdl.handle.net/20.500.11937/23209 |