Number and brightness analysis of sFRP4 domains in live cells demonstrates vesicle association signal of the NLD domain and dynamic intracellular responses to Wnt3a

The Wnts are secreted, lipidated glycoproteins that play a role in cellular processes of differentiation, proliferation, migration, survival, polarity and stem cell self-renewal. The majority of Wnts biological effects are through binding to specific frizzled (Fzd) receptor complexes leading to acti...

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Bibliographic Details
Main Authors: Perumal, V., Krishnan, K., Gratton, E., Dharmarajan, Arunasalam, Fox, Simon
Format: Journal Article
Published: Elsevier Ltd 2015
Online Access:http://hdl.handle.net/20.500.11937/22787