Balanced globin protein expression and heme biosynthesis improve production of human hemoglobin in Saccharomyces cerevisiae

Due to limitations associated with whole blood for transfusions (antigen compatibility, transmission of infections, supply and storage), the use of cell-free hemoglobin as an oxygen carrier substitute has been in the center of research interest for decades. Human hemoglobin has previously been synth...

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Bibliographic Details
Main Authors: Liu, Lifang, Martínez, J., Liu, Z., Petranovic, D., Nielsen, J.
Format: Journal Article
Published: Academic Press Inc. 2014
Online Access:http://hdl.handle.net/20.500.11937/22603