Enzymatic Deracemization of (R,S)-Ibuprofen Ester via Lipase-catalyzed Membrane Reactor

Enzymatic Deracemization of (R,S)-Ibuprofen Ester via Lipase-catalyzed Membrane Reactor

Ibuprofen (isobutyl-propanoic-phenolic acid) is a chiral drug which essentially well-known for its analgesic, antipyretic and anti-inflammatory effects. In the present work, an enzymatic membrane reactor (EMR) has been developed for the production of optically pure (S)-ibuprofen acid. The EMR is equ...

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Bibliographic Details
Main Authors: Lau, Sie Yon, Gonawan, Fadzil, Kamaruddin, Azlina, Uzir, Mohamad
Format: Journal Article
Published: American Chemical Society 2013
Subjects:
S)-Ibuprofen ester
(R
enantiomeric excess
racemization
enzymatic membrane reactor
Dynamic kinetic resolution
Online Access:http://hdl.handle.net/20.500.11937/22240

Internet

http://hdl.handle.net/20.500.11937/22240

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