Pseudomonas aeruginosa Alkyl quinolones repress hypoxia-inducible factor 1 (HIF-1) signaling through HIF-1a degradation

The transcription factor hypoxia-inducible factor 1 (HIF-1) has recently emerged to be a crucial regulator of the immune response following pathogen perception, including the response to the important human pathogen Pseudomonas aeruginosa. However, as mechanisms involved in HIF-1 activation by bacte...

Full description

Bibliographic Details
Main Authors: Legendre, C., Reen, F., Mooij, M., McGlacken, G., Adams, C., O'Gara, Fergal
Format: Journal Article
Published: American Society for Microbiology 2012
Online Access:http://hdl.handle.net/20.500.11937/22150