Glucose metabolism is required for oxidized LDL-induced macrophage survival: Role of PI3K and Bcl-2 family proteins

OBJECTIVE-: Oxidized low-density lipoprotein (oxLDL) induces survival of colony stimulating factor-1 (CSF-1)-dependent macrophages in vitro. Because atherosclerotic lesion-associated macrophages take up large amounts of glucose, we investigated whether, and how, oxLDL promotes glucose uptake and how...

Full description

Bibliographic Details
Main Authors: Elsegood, Caryn, Chang, M., Jessup, W., Scholz, G., Hamilton, J.
Format: Journal Article
Published: Lippincott Williams & Wilkins 2009
Online Access:http://hdl.handle.net/20.500.11937/21809