Environmental determinants - The role of GSTP1 polymorphisms and tobacco smoke exposure in children with acute asthma

Background. The glutathione S-transferase enzymes (GSTs) play an important role in the detoxification of environmental tobacco smoke (ETS), which contributes to airway inflammation, a key component of asthma. Genetic variation in GST genes may influence individuals' ability to detoxify environm...

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Bibliographic Details
Main Authors: Schultz, E., Devadason, S., Khoo, S., Zhang, Guicheng, Bizzintino, J., Martin, A., Goldblatt, J., Laing, I., Le Souf, P., Hayden, C.
Format: Journal Article
Published: Informa Healthcare 2010
Online Access:http://hdl.handle.net/20.500.11937/21760