Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo

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Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo

Background: Constitutive activation of signal transducer and activator of transcription 3 (STAT3) has been linked with proliferation, survival, invasion and angiogenesis of a variety of human cancer cells, including hepatocellular carcinoma (HCC). Thus, novel agents that can suppress STAT3 activatio...

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Bibliographic Details
Main Authors:	Sethi, G., Chatterjee, S., Rajendran, P., Li, F., Shanmugam, M., Wong, K., Kumar, Alan Prem, Senapati, P., Behera, A., Hui, K., Basha, J., Natesh, N., Luk, J., Kundu, T.
Format:	Journal Article
Published:	BioMed Central Ltd. 2014
Subjects:	Acetylation Apoptosis Garcinol STAT3 HCC
Online Access:	http://hdl.handle.net/20.500.11937/21716

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