TLR3 and RIG-I gene variants: Associations with functional effects on receptor expression and responses to measles virus and vaccine in vaccinated infants

Measles virus causes severe morbidity and mortality, despite the availability of measles vaccines. Successful defence against viral pathogens requires early recognition of virus-specific patterns by innate receptors like Toll-like receptor (TLR)3 and the RNA helicase, retinoic acid inducible gene-I...

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Bibliographic Details
Main Authors: Clifford, H., Yerkovich, S., Khoo, S., Zhang, Guicheng, Upham, J., Le Souëf, P., Richmond, P., Hayden, C.
Format: Journal Article
Published: 2012
Online Access:http://hdl.handle.net/20.500.11937/21346