Selective binding and release of aspirin by an encapsulating receptor

The selective binding of aspirin deep inside superbowl synthetic hosts is reported. Evidence for a two-point binding mode of the drug by the host is presented. Both the strength of aspirin binding and the rate of its release are manipulated by altering the substituents about the host’s aperture

Bibliographic Details
Main Authors: Nguyen, Thanh Vinh, Yoshida, H., Sherburn, M.
Format: Journal Article
Published: The Royal Society of Chemistry 2010
Online Access:http://pubs.rsc.org/en/Content/ArticleLanding/2010/CC/c0cc00422g#!divAbstract
http://hdl.handle.net/20.500.11937/20571