Wnt antagonist, secreted frizzled-related protein 4 (sFRP4), increases chemotherapeutic response of glioma stem-like cells

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Wnt antagonist, secreted frizzled-related protein 4 (sFRP4), increases chemotherapeutic response of glioma stem-like cells

Malignant gliomas have a highly tumorigenic subpopulation, termed cancer stem cells (CSCs), that drives tumor formation and proliferation. CSCs possess inherent resistance mechanisms against radiation- and chemotherapy- induced cancer cell death, enabling them to survive and initiate tumor recurrenc...

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Bibliographic Details
Main Authors:	Warrier, S., Balu, S., Kumar, Alan Prem, Michael, M., Dharmarajan, Arunasalam
Format:	Journal Article
Published:	Cognizant Communication Corporation 2014
Subjects:	Secreted frizzled-related protein 4 (sFRP4) Apoptosis Glioma stem cells (GSCs) Chemosensitivity Wnt antagonist
Online Access:	http://hdl.handle.net/20.500.11937/20326

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