Wnt antagonist, secreted frizzled-related protein 4 (sFRP4), increases chemotherapeutic response of glioma stem-like cells
Malignant gliomas have a highly tumorigenic subpopulation, termed cancer stem cells (CSCs), that drives tumor formation and proliferation. CSCs possess inherent resistance mechanisms against radiation- and chemotherapy- induced cancer cell death, enabling them to survive and initiate tumor recurrenc...
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Published: |
Cognizant Communication Corporation
2014
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/20326 |