Latrepirdine (Dimebon™) enhances autophagy and reduces intracellular GFP-A42 levels in yeast

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Latrepirdine (Dimebon™) enhances autophagy and reduces intracellular GFP-A42 levels in yeast

Latrepirdine (Dimebon™), an anti-histamine, has shown some benefits in trials of neurodegenerative diseases characterized by accumulation of aggregated or misfolded protein such as Alzheimer’s disease (AD) and has been shown to promote the removal of α-synuclein protein aggregates in vivo. An import...

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Bibliographic Details
Main Authors:	Bharadwaj, P., Verdile, Giuseppe, Barr, R., Gupta, V., Steele, J., Lachenmayer, M., Yue, Z., Ehrlich, M., Petsko, G., Ju, S., Ringe, D., Sankovich, S., Caine, J., Macreadie, I., Gandy, S., Martins, R.
Format:	Journal Article
Published:	IOS Press 2012
Online Access:	http://hdl.handle.net/20.500.11937/20298

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