Latrepirdine (Dimebon™) enhances autophagy and reduces intracellular GFP-A42 levels in yeast
Latrepirdine (Dimebon™), an anti-histamine, has shown some benefits in trials of neurodegenerative diseases characterized by accumulation of aggregated or misfolded protein such as Alzheimer’s disease (AD) and has been shown to promote the removal of α-synuclein protein aggregates in vivo. An import...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Journal Article |
| Published: |
IOS Press
2012
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| Online Access: | http://hdl.handle.net/20.500.11937/20298 |