The Role of Secreted Frizzled Related Protein 4 (sFRP-4) in Regulating Oestradiol-Induced Growth of the MCF-7 Breast Cancer Cell Line

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The Role of Secreted Frizzled Related Protein 4 (sFRP-4) in Regulating Oestradiol-Induced Growth of the MCF-7 Breast Cancer Cell Line

The Wnt signalling pathway is involved in regulating cellular proliferation and differentiation, and aberrant activation has been described in several cancers including breast. Oestradiol up regulates Wnt pathway gene expression, and thereby activates the Wnt signalling pathway. We used the oestroge...

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Bibliographic Details
Main Authors:	McLaren, S., Arfuso, Frank, Zeps, N., Dharmarajan, Arunasalam
Format:	Journal Article
Published:	Lifescience Global 2014
Subjects:	β-catenin cellular proliferation Wnt signalling oestradiol sFRP4 Breast cancer growth inhibition
Online Access:	http://hdl.handle.net/20.500.11937/20199

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