The Role of Secreted Frizzled Related Protein 4 (sFRP-4) in Regulating Oestradiol-Induced Growth of the MCF-7 Breast Cancer Cell Line

The Role of Secreted Frizzled Related Protein 4 (sFRP-4) in Regulating Oestradiol-Induced Growth of the MCF-7 Breast Cancer Cell Line

The Wnt signalling pathway is involved in regulating cellular proliferation and differentiation, and aberrant activation has been described in several cancers including breast. Oestradiol up regulates Wnt pathway gene expression, and thereby activates the Wnt signalling pathway. We used the oestroge...

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Bibliographic Details
Main Authors: McLaren, S., Arfuso, Frank, Zeps, N., Dharmarajan, Arunasalam
Format: Journal Article
Published: Lifescience Global 2014
Subjects:
β-catenin
cellular proliferation
Wnt signalling
oestradiol
sFRP4
Breast cancer
growth inhibition
Online Access:http://hdl.handle.net/20.500.11937/20199

Internet

http://hdl.handle.net/20.500.11937/20199

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