Biologically active core/shell nanoparticles self-assembled from cholesterol-terminated PEG-TAT for drug delivery across the blood-brain barrier

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Biologically active core/shell nanoparticles self-assembled from cholesterol-terminated PEG-TAT for drug delivery across the blood-brain barrier

Biologically active polymer core/shell nanoparticles (i.e. micelles) self-assembled from TAT-poly(ethylene glycol) (PEG)-b-cholesterol (TAT-PEG-b-Chol) were fabricated and used as carrier for targeted blood-brain barrier delivery of antibiotics. Ciprofloxacin as a model antibiotic was efficiently lo...

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Bibliographic Details
Main Authors:	Liu, Lihong, Guo, K., Lu, J., Venkatraman, S., Luo, D., Ng, K., Ling, E., Moochhala, S., Yang, Y.
Format:	Journal Article
Published:	Elsevier Ltd 2008
Online Access:	http://hdl.handle.net/20.500.11937/20181

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