Biologically active core/shell nanoparticles self-assembled from cholesterol-terminated PEG-TAT for drug delivery across the blood-brain barrier
Biologically active polymer core/shell nanoparticles (i.e. micelles) self-assembled from TAT-poly(ethylene glycol) (PEG)-b-cholesterol (TAT-PEG-b-Chol) were fabricated and used as carrier for targeted blood-brain barrier delivery of antibiotics. Ciprofloxacin as a model antibiotic was efficiently lo...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
| Published: |
Elsevier Ltd
2008
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| Online Access: | http://hdl.handle.net/20.500.11937/20181 |