The self-association of High Mobility Group Box 1 (HMGB1): Implications for interaction with Receptor for Advanced Glycation End-products (RAGE) and DNA
High Mobility Group Box 1 (HMGB1) plays key roles in inflammatory diseases including cancer and diabetes. Intracellularly, HMGB1 binds DNA and assists transcription. Extracellularly, HMGB1 promotes inflammatory responses by binding to receptors such as the Receptor of Advanced Glycation End-products...
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| Format: | Thesis |
| Language: | English |
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Curtin University
2015
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| Online Access: | http://hdl.handle.net/20.500.11937/2004 |