QR Code

Expression Profile of Wnt/β-Catenin Signalling Molecules and the Wnt Antagonist Secreted Frizzled-Related Protein 4 in Apoptosis in Breast Cancer Tissue Micro-Arrays

Wnt proteins are often up-regulated in cancer. The secreted frizzled-related proteins (sFRPs) can abrogate Wnt signalling and are involved in apoptosis. We investigated the expression of Wnt1, β-Catenin, and an antagonist, sFRP4, as well as apoptosis in breast cancer using tissue micro-arrays (TMAs)...

Full description

Bibliographic Details
Main Authors:	Berry, A., Charles, A., Zeps, N., Cregan, D., Arfuso, Frank, Dharmarajan, Arunasalam
Format:	Journal Article
Published:	Lifescience Global 2014
Subjects:	Wnt secreted frizzled-related protein 4 Breast tissue micro-arrays cancer
Online Access:	http://hdl.handle.net/20.500.11937/19312

Similar Items

Wnt antagonist, secreted frizzled-related protein 4 (sFRP4), increases chemotherapeutic response of glioma stem-like cells
by: Warrier, S., et al.
Published: (2014)

Secreted Frizzled-Related Protein 4 expression is positively associated with responsiveness to Cisplatin of ovarian cancer cell lines in vitro and with lower tumour grade in mucinous ovarian cancers
by: Saran, U., et al.
Published: (2012)

Breast cancer stem-like cells are inhibited by diosgenin, a steroidal saponin, by the attenuation of the Wnt ß-catenin signaling via the Wnt antagonist secreted frizzled related protein-4
by: Bhuvanalakshmi, G., et al.
Published: (2017)

Expression profile and function of Wnt signaling mechanisms in malignant mesothelioma cells
by: Fox, Simon, et al.
Published: (2013)

Wnt antagonist secreted frizzled-related protein 4 upregulates adipogenic differentiation in human adipose tissue-derived mesenchymal stem cells
by: Visweswaran, Malini, et al.
Published: (2015)

The Role of Secreted Frizzled Related Protein 4 (sFRP-4) in Regulating Oestradiol-Induced Growth of the MCF-7 Breast Cancer Cell Line
by: McLaren, S., et al.
Published: (2014)

The roles of WNT1 and DKK1 during in vitro neural differentiation of mouse embryonic stem cell lines
by: Gao, Liyang
Published: (2013)

The Effects of Combination Treatment Using Phenoxodiol and Docetaxel, and Phenoxodiol and Secreted Frizzled-related Protein 4 on Prostate Cancer Cell Lines
by: Mahoney, S., et al.
Published: (2014)

Wnt antagonist, secreted frizzled-related protein 4 (SFRP4) and peptides from its associated domains, increases chemotherapeutic response of cancer stem cells of malignant mesothelioma cell lines
by: Perumal, V., et al.
Published: (2017)

Therapeutic approach to target mesothelioma cancer cells using the Wnt antagonist, secreted frizzled-related protein 4: Metabolic state of cancer cells
by: Perumal, Vanathi, et al.
Published: (2015)

Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma
by: Bhuvanalakshmi, G., et al.
Published: (2019)

Structure-based prediction of Wnt binding affinities for Frizzled-type cysteine-rich domain
by: Agostino, M., et al.
Published: (2017)

Multi-lineage differentiation of mesenchymal stem cells - To Wnt, or not Wnt
by: Visweswaran, Malini, et al.
Published: (2015)

The role of the cysteine-rich domain and netrin-like domain of secreted frizzled-related protein 4 in angiogenesis inhibition in vitro
by: Longman, D., et al.
Published: (2012)

Role of Wnt signalling in early pregnancy
by: Nayeem, S., et al.
Published: (2015)

Wnt/ß-Catenin Signalling during Liver Metabolism, Chronic Liver Disease and Hepatocarcinogenesis
by: Shirolkar, Gayatri, et al.
Published: (2018)

SFRP-4 abrogates Wnt-3a-induced ß-catenin and Akt/PKB signalling and reverses a Wnt-3a-imposed inhibition of in vitro mammary differentiation
by: Constantinou, T., et al.
Published: (2008)

The role of Wnt signalling in angiogenesis
by: Olsen, J., et al.
Published: (2017)

Secreted frizzled-related protein 4 and its implications in cancer and apoptosis
by: Pohl, S., et al.
Published: (2015)

Swap70b is required for convergent and extension cell movement during zebrafish gastrulation linking Wnt11 signalling and RhoA effector function
by: Xu, Xiaoou, et al.
Published: (2014)

Wnt signaling in triple-negative breast cancer
by: Pohl, S., et al.
Published: (2017)

Wnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approaches
by: Onyido, Emenike K., et al.
Published: (2016)

Paracrine communication modulates production of Wnt antagonists and COX1-mediated prostaglandins in a decidual-trophoblast co-culture model
by: Nayeem, S., et al.
Published: (2015)

The Wnt regulator SFRP4 inhibits mesothelioma cell proliferation, migration, and antagonizes Wnt3a via its netrin-like domain
by: Perumal, Vanathi, et al.
Published: (2017)

Secreted frizzled related proteins: Implications in cancers
by: Surana, R., et al.
Published: (2014)

Secreted frizzled related proteins: Implications in cancers
by: Surana, R., et al.
Published: (2014)

Cancer stem-like cells from head and neck cancers are chemosensitized by the Wnt antagonist, sFRP4, by inducing apoptosis, decreasing stemness, drug resistance and epithelial to mesenchymal transition
by: Warrier, Sudha, et al.
Published: (2014)

Secreted frizzled-related protein 4: An angiogenesis inhibitor
by: Muley, A., et al.
Published: (2010)

Regulation of cancer stem cell metabolism by secreted frizzled-related protein 4 (SFRP4)
by: Deshmukh, Abhijeet, et al.
Published: (2018)

Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5+ stem cells
by: Flanagan, D., et al.
Published: (2015)

Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo
by: Flanagan, D., et al.
Published: (2017)

The role of the WNT/β-catenin pathway in central nervous system primitive neuroectodermal tumours (CNS PNETs)
by: Rogers, H.A., et al.
Published: (2013)

SFRP-mediated Wnt sequestration as a potential therapeutic target for Alzheimer's disease
by: Warrier, Sudha, et al.
Published: (2016)

Epigenetic regulation of the secreted frizzled-related protein family in human glioblastoma multiforme
by: Schiefer, L., et al.
Published: (2014)

The Philippines stingless bee propolis promotes hair growth through activation of Wnt/β-catenin signaling pathway
by: Tang, Yulan, et al.
Published: (2022)

The effects of cannabinoids on insulin secretion
by: Anderson, Richard L.
Published: (2011)

The inhibitory influence of adipose tissue-derived mesenchymal stem cell environment and Wnt antagonism on breast tumour cell lines
by: Visweswaran, M., et al.
Published: (2017)

Epigenetic reprogramming converts human Wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators
by: Bhuvanalakshmi, G., et al.
Published: (2017)

The role of Wnt/β-catenin signalling in the regulation of liver progenitor cell responses in non-alcoholic fatty liver disease
by: Shirolkar, Gayatri Dhananjay
Published: (2021)

Secreted Frizzled related protein-4 (sFRP4) promotes epidermal differentiation and apoptosis
by: Maganga, R., et al.
Published: (2008)

Cannot write session to /tmp/vufind_sessions/sess_0ta5lksuiiqhi3n1sddatk4fa7