Expression Profile of Wnt/β-Catenin Signalling Molecules and the Wnt Antagonist Secreted Frizzled-Related Protein 4 in Apoptosis in Breast Cancer Tissue Micro-Arrays

Wnt proteins are often up-regulated in cancer. The secreted frizzled-related proteins (sFRPs) can abrogate Wnt signalling and are involved in apoptosis. We investigated the expression of Wnt1, β-Catenin, and an antagonist, sFRP4, as well as apoptosis in breast cancer using tissue micro-arrays (TMAs)...

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Bibliographic Details
Main Authors: Berry, A., Charles, A., Zeps, N., Cregan, D., Arfuso, Frank, Dharmarajan, Arunasalam
Format: Journal Article
Published: Lifescience Global 2014
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/19312