Systemically administered PEDF against primary and secondary tumours in a clinically relevant osteosarcoma model

Background: Pigment epithelium-derived factor (PEDF) is an endogenous glycoprotein with a potential role as a therapeutic for osteosarcoma. Animal studies have demonstrated the biological effects of PEDF on osteosarcoma; however, these results are difficult to extrapolate for human use due to the ch...

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Bibliographic Details
Main Authors: Broadhead, M., Dass, Crispin, Choong, P.
Format: Journal Article
Published: Nature Publishing Group 2011
Online Access:http://hdl.handle.net/20.500.11937/19073