Insights into the critical role of NADPH oxidase(s) in the normal and dysregulated pancreatic beta cell

It is now widely accepted that reactive oxygen species (ROS) contribute to cell and tissue dysfunction and damage in diabetes. The source of ROS in the insulin secreting pancreatic beta cells has traditionally been considered to be the mitochondrial electron transport chain. While this source is und...

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Bibliographic Details
Main Authors: Newsholme, Philip, Morgan, D., Rebelato, E., Oliveira-Emilio, H., Procopio, J., Curi, R., Carpinelli, A.
Format: Journal Article
Published: Springer Verlag 2009
Online Access:http://hdl.handle.net/20.500.11937/18782