Secreted frizzled-related protein 4 and its implications in cancer and apoptosis

Secreted frizzled-related protein 4 (SFRP4) is a glycoprotein that acts as an antagonist of Wnt ligands, causing inhibition of the canonical Wnt signalling pathway. First noticed due to high expression levels during times of increased apoptosis, SFRP4 has been implicated in cell proliferation and di...

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Bibliographic Details
Main Authors: Pohl, S., Scott, R., Arfuso, Frank, Perumal, V., Dharmarajan, Arunasalam
Format: Journal Article
Published: Kluwer Academic Publishers 2015
Online Access:http://hdl.handle.net/20.500.11937/17677