Synthesis of biodegradable polymer-mesoporous silica composite microspheres for DNA prime-protein boost vaccination

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Synthesis of biodegradable polymer-mesoporous silica composite microspheres for DNA prime-protein boost vaccination

DNA vaccines or proteins are capable of inducing specific immunity; however, the translation to the clinic has generally been problematic, primarily due to the reduced magnitude of immune response and poor pharmacokinetics. Herein we demonstrate a composite microsphere formulation, composed of mesop...

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Bibliographic Details
Main Authors:	Ho, J., Huang, Y., Danquah, Michael, Wang, H., Forde, G.
Format:	Journal Article
Published:	Elsevier Science 2010
Online Access:	http://hdl.handle.net/20.500.11937/17451

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