Synthesis of biodegradable polymer-mesoporous silica composite microspheres for DNA prime-protein boost vaccination
DNA vaccines or proteins are capable of inducing specific immunity; however, the translation to the clinic has generally been problematic, primarily due to the reduced magnitude of immune response and poor pharmacokinetics. Herein we demonstrate a composite microsphere formulation, composed of mesop...
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Published: |
Elsevier Science
2010
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| Online Access: | http://hdl.handle.net/20.500.11937/17451 |