Bile signalling promotes chronic respiratory infections and antibiotic tolerance

Despite aggressive antimicrobial therapy, many respiratory pathogens persist in the lung, underpinning the chronic inflammation and eventual lung decline that are characteristic of respiratory disease. Recently, bile acid aspiration has emerged as a major comorbidity associated with a range of lung...

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Bibliographic Details
Main Authors: Reen, F., Flynn, S., Woods, D., Dunphy, N., Chróinín, M., Mullane, D., Stick, S., Adams, C., O'Gara, Fergal
Format: Journal Article
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/20.500.11937/17382