Inhibition of OCTN2-mediated transport of carnitine by etoposide
OCTN2 is a bifunctional transporter that reabsorbs filtered carnitine in a sodium-dependent manner andsecretes organic cations into urine as a proton antiport mechanism. We hypothesized that inhibition of OCTN2 by anticancer drugs can influence carnitine resorption. OCTN2-mediated transport inhibiti...
| Main Authors: | , , , , , , , |
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| Format: | Journal Article |
| Published: |
American Association for Cancer Research
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/15970 |