An investigation of p53’s differential activation of cell cycle arrest and apoptosis
The p53 tumour suppressor protein lies at the hub of a very complex network of cellular pathways including apoptosis, cell cycle arrest, DNA repair and cellular senescence. However, the mechanism of why and how p53 switches between apoptosis and cell cycle arrest, thereby determining a cell’s fate,...
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| Format: | Thesis |
| Language: | English |
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Curtin University
2008
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| Online Access: | http://hdl.handle.net/20.500.11937/1577 |