The role of the sFRP4 protein in modulation of cancer growth and anti-neoplastic drug sensitivity

This project found that reintroducing a regulatory protein, sFRP4, to mesothelioma cancer cell models could inhibit their growth, ability to migrate and induce a form of cell death. In addition sFRP4 could sensitise mesothelioma cells to drug treatment. The mechanisms involved were studied in detai...

Full description

Bibliographic Details
Main Author: Perumal, Vanathi
Format: Thesis
Language:English
Published: Curtin University 2014
Online Access:http://hdl.handle.net/20.500.11937/1548