Transformation of Aspergillus based on the hygromycin B resistance marker from Escherichia coli

A new, heterologous, dominant marker for selection of Aspergillus transformants is described. This marker is based on the Escherichia coli hygromycin B (HmB) phosphotransferase gene (hph). Expression of the hph gene is controlled by A. nidulans gpd and trpC expression signals. An Aspergillus transfo...

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Bibliographic Details
Main Authors: Punt, P., Oliver, Richard, Dingemanse, M., Pouwels, P., Van Den Hondel, C.
Format: Journal Article
Published: 1987
Online Access:http://hdl.handle.net/20.500.11937/14903