Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers

Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers

Platinum compounds such as cisplatin and carboplatin are frequently used as the first-line chemotherapy for the treatment of the head and neck squamous cell carcinoma (HNSCC). In the present study, we investigated whether garcinol, a polyisoprenylated benzophenone can chemosensitize HNSCC to cisplat...

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Bibliographic Details
Main Authors: Li, F., Shanmugam, M., Siveen, K., Wang, F., Ong, T., Loo, S., Swamy, M., Mandal, S., Kumar, Alan Prem, Goh, B., Kundu, T., Ahn, K., Wang, L., Hui, K., Sethi, Gautam
Format: Journal Article
Published: Impact Journals LLC 2015
Online Access:http://hdl.handle.net/20.500.11937/14687

Internet

http://hdl.handle.net/20.500.11937/14687

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