Mathematical Model of Metabolism and Electrophysiology of Amino Acid and Glucose Stimulated Insulin Secretion: In Vitro Validation Using a β-Cell Line
We integrated biological experimental data with mathematical modelling to gain insights into the role played by L-alanine in amino acid-stimulated insulin secretion (AASIS) and in D-glucose-stimulated insulin secretion (GSIS), details important to the understanding of complex β-cell metabolic coupli...
| Main Authors: | , , |
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| Format: | Journal Article |
| Published: |
Public Library of Science
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/14659 |