The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets

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The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets

In blood platelets, stimulation of G protein-coupled receptors (GPCRs) by thrombin triggers the activation of Src family kinases (SFKs), resulting in the tyrosine-phosphorylation of multiple substrates, but the mechanism underlying this process is still poorly understood. In the present study, we sh...

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Bibliographic Details
Main Authors:	Canobbio, I., Cipolla, L., Guidetti, G., Manganaro, D., Visconte, C., Kim, S., Okigaki, M., Falasca, Marco, Kunapuli, S., Torti, M.
Format:	Journal Article
Published:	Portland Press Ltd 2015
Online Access:	http://hdl.handle.net/20.500.11937/14640

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