The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets
In blood platelets, stimulation of G protein-coupled receptors (GPCRs) by thrombin triggers the activation of Src family kinases (SFKs), resulting in the tyrosine-phosphorylation of multiple substrates, but the mechanism underlying this process is still poorly understood. In the present study, we sh...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal Article |
| Published: |
Portland Press Ltd
2015
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| Online Access: | http://hdl.handle.net/20.500.11937/14640 |