The Role of Presenilin and its Interacting Proteins in the Biogenesis of Alzheimer’s Beta Amyloid
The biogenesis and accumulation of the beta amyloid protein (Aß) is a key event in the cascade of oxidative and inflammatory processes that characterises Alzheimer’s disease. The presenilins and its interacting proteins play a pivotal role in the generation of Aß from the amyloid precursor protein (...
| Main Authors: | Verdile, Giuseppe, Gandy, S., Martins, R. |
|---|---|
| Format: | Journal Article |
| Published: |
Kluwer Academic Publishers-Plenum Publishers
2007
|
| Online Access: | http://hdl.handle.net/20.500.11937/14145 |
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