The Role of Presenilin and its Interacting Proteins in the Biogenesis of Alzheimer’s Beta Amyloid

The biogenesis and accumulation of the beta amyloid protein (Aß) is a key event in the cascade of oxidative and inflammatory processes that characterises Alzheimer’s disease. The presenilins and its interacting proteins play a pivotal role in the generation of Aß from the amyloid precursor protein (...

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Bibliographic Details
Main Authors: Verdile, Giuseppe, Gandy, S., Martins, R.
Format: Journal Article
Published: Kluwer Academic Publishers-Plenum Publishers 2007
Online Access:http://hdl.handle.net/20.500.11937/14145