Stability and Release Kinetics of an Advanced Gliclazide-Cholic Acid Formulation: The Use of Artificial-Cell Microencapsulation in Slow Release Targeted Oral Delivery of Antidiabetics

Stability and Release Kinetics of an Advanced Gliclazide-Cholic Acid Formulation: The Use of Artificial-Cell Microencapsulation in Slow Release Targeted Oral Delivery of Antidiabetics

Introduction: In previous studies carried out in our laboratory, a bile acid (BA) formulation exerted a hypoglycaemic effect in a rat model of type-1 diabetes (T1D). When the antidiabetic drug gliclazide (G) was added to the bile acid, it augmented the hypoglycaemic effect. In a recent study, we des...

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Bibliographic Details
Main Authors: Mooranian, Armin, Negrulj, Rebecca, Mathavan, Sangeetha, Martinez, Jorge, Sciarretta, Jessica, Chen-Tan, Nigel, Mukkur, Trilochan, Mikov, Momir, Lalic-Popovic, M., Stojancevic, M., Golocorbin-Kon, S., Al-Salami, Hani
Format: Journal Article
Published: Springer New York LLC 2014
Subjects:
Bile acid
Gliclazide
Artificial-cell microencapsulation
Diabetes
Online Access:http://hdl.handle.net/20.500.11937/14090

Internet

http://hdl.handle.net/20.500.11937/14090

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