Factors affecting metformin plasma concentrations

Background: According to the United Kingdom prospective diabetes study, metformin is considered the drug of choice in overweight newly diagnosed type 2 diabetic patients. Metformin is well characterized as a substrate of the organic cation transporter (OCT) 1 and OCT 2. In vitro and in vivo studies...

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Bibliographic Details
Main Author: Alawadhi, Sohaila
Format: Thesis
Language:English
Published: Curtin University 2010
Online Access:http://hdl.handle.net/20.500.11937/1383