Cultivation of E. coli carrying a plasmid-based Measles vaccine construct (4.2 kbp pcDNA3F) employing medium optimisation and pH-temperature induction techniques

Background: Plasmid-based measles vaccines offer great promises over the conventional fertilised egg method such as ease of manufacture and mimic wild-type intracellular antigen expression. The increasing number of clinical trials on plasmid-based measles vaccines has triggered the need to make more...

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Bibliographic Details
Main Authors: Ongkudon, C., Pickering, R., Webster, D., Danquah, Michael
Format: Journal Article
Published: 2011
Online Access:http://hdl.handle.net/20.500.11937/13753